MMSL - In Press

EFFECTIVE FORWARDED SURGICAL CARE IN THE ARMY OF THE CZECH REPUBLIC AND THE WORLDReview article

Jan Brixi

MMSL X:X | DOI: 10.31482/mmsl.2025.001  

This topic is probably the most important in the field of military healthcare in the long term, because care of this nature is the very reason why the whole sector was created. Effective forwarded surgical care is a crucial factor in reducing preventable battlefield casualties, known and developed since the historical beginnings of military healthcare. This highly demanding medical discipline is an absolutely essential component of the modern war effort, in which it takes on a whole new dimension thanks to unimaginable technological, medical and military-tactical progress. The changed character of the world's main battlefields seems to be crucial at...

TRENDS IN ORAL ANTICOAGULANT PRESCRIPTION PATTERNS IN THE CZECH REPUBLIC: A RETROSPECTIVE ANALYSIS OF 2019–2024Original article

Tomas Veleta, Jiri Vlcek, Jiri Cyrany, Radovan Maly, Tomas Soukup

MMSL X:X | DOI: 10.31482/mmsl.2025.002  

Background: The patterns of oral anticoagulant (OAC) prescription have significantly changed in recent years, with direct oral anticoagulants (DOACs) gradually replacing warfarin. While this transition occurred earlier in some countries, limited data are available about its timeline in the Czech Republic.Objectives: This study aimed to analyse trends in OAC prescriptions in the Czech Republic from 2019 to 2024, focusing on the shift from warfarin to DOACs and the patterns of utilisation of individual DOACs.Methods: A retrospective analysis was conducted using national electronic prescription data from the State Institute for Drug Control (SÚKL). Annual...

RESILIENT PLATFORM FOR MICROBIOME DATABASES: ESSENTIAL ATTRIBUTESReview article

Tomáš Ráčil, Petr Františ, Alexandr Štefek

MMSL X:X | DOI: 10.31482/mmsl.2025.003  

The rapid growth of microbiome research is hindered by significant challenges in data management, including data fragmentation across disparate silos, a lack of methodological standardization, and barriers to advanced privacy-preserving analysis. To address these issues, this article proposes a conceptual architectural blueprint for a resilient, scalable, and integrated platform for microbiome data. Our proposed architecture is a modular, cloud-native system designed to support the entire research lifecycle. Key attributes include a multi-layered microservices framework to ensure scalability, adherence to FAIR (Findable, Accessible, Interoperable,...

BLOOD DONOR MOTIVATION IN THE CONTEXT OF SOCIODEMOGRAPHIC CHARACTERISTICS AND MOTIVATIONAL FACTORSOriginal article

Pavlína Rabasová, Karel Pavlica, Roman Pospíšil, Hana Konečná, Zuzana Čermáková

MMSL X:X | DOI: 10.31482/mmsl.2025.004  

Introduction: The motivation of donors to donate substances of human origin, such as blood and its components, bone marrow, gametes, and others, is influenced by various factors, such as sociodemographic characteristics, motivational factors, and the level of social competence.Aim: To describe and analyse the motivation of donors to donate blood and blood components in relation to sociodemographic characteristics and motivational factors at the Blood Centre of the University Hospital Ostrava.Design and Methods: Quantitative research based on an anonymous questionnaire survey, followed by inferential analysis of bivariate data. The self-designed questionnaire...

MAPPING CHALLENGES, STRATEGIS, AND PREPAREDNESS NEEDS OF ESSENTIAL SERVICES DURING THE COVID-19 PANDEMIC AND FUTURE VIRAL SERVICESOriginal article

Vanda Bostik, Aneta Markova, Radka Prazdna, Adela Mojzisova, Petra Bendova, Ivana Havrankova, Zuzana Truhlarova, Pavel Zikl

MMSL X:X | DOI: 10.31482/mmsl.2025.005  

This study is based on a detailed analysis of the challenges faced by various social services in the Czech Republic during the COVID-19 pandemic. The study took into account a combination of several different data sources and included an analysis of recommendations issued during the pandemic, data from preliminary research conducted among social service providers, a questionnaire survey, and two-phase qualitative focus group interviews. Data on residential, outpatient, and field social services in the Czech Republic were collected. The main objective of the research was to map the difficulties these services faced, their working strategies and responses...

MODULATION OF AUTISM SYMPTOMS IN A 13-YEAR-OLD BOY BY FOOD SUPPLEMENT JUVENILCase report

Jela Hrnciarova, Anna Hanusova, Tereza Horakova, Josef Fusek, Klara Kubelkova, Ales Macela

MMSL X:X | DOI: 10.31482/mmsl.2025.006  

Antidepressants, antipsychotics, anti-anxiety drugs, or sleeping pills are most often used to treat autism spectrum disorders. The treatment thus focuses on the manifestations accompanying autism, such as inattention, irritability, or sleep disorders, but does not address the essence of the social deficits of autistic children. In addition, drug treatment is often poorly tolerated. Since a certain association of autism with gut microbiota dysbiosis has been demonstrated, and given the existence of the microbiota-gut-brain axis, it can be assumed that modulation of the gut microbiota could contribute to the treatment of the essence of some Autism Spectrum...